On System Center Data Protection Manager (DPM) 2010 with March 2011 hotfix I got the following error when backing up to tape:
ID 30101 Details: The request could not be performed because of an I/O device error (0x8007045D)
This is an error that was originally fixed in DPM 2007 with a hotfix http://support.microsoft.com/kb/970868 , but reappeared on my 2010 install. It can occur with large tape backups that span more than one tape. I fixed the error by adding the following registry key, a reboot wasn’t necessary:
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Microsoft Data Protection Manager\Agent] "BufferQueueSize"=dword:00000001
I’ve had the same problem with DPM 2012 SP1 and the registry still fix worked.