Following the installation of an Outlook add-in I received the message “Cannot start Microsoft Outlook” when I attempted to open Outlook.

I tried to open Outlook in Safe Mode by holding down CTRL when clicking the Outlook icon.  However, this didn’t solve the problem.  Next I opened Control Panel and received the message “Your system needs more memory or system resources”.  This didn’t make sense as I had GBs of free RAM.

In order to solve the problem, I opened registry editor and renamed

HKCU\Software\Microsoft\Windows NT\CurrentVersion\Windows Messaging Subsystem

to Windows Messaging Subsystem – BAK.  I was then able to open Outlook and create a new profile.